3kze

X-ray diffraction
1.8Å resolution

Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in Complex With SSRKEYYA Peptide

Released:

Function and Biology Details

Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-163718 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rho guanine nucleotide exchange factor TIAM1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 94 amino acids
Theoretical weight: 10.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13009 (Residues: 841-930; Coverage: 6%)
Gene name: TIAM1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Synthetic Peptide Chains: D, E
Molecule details ›
Chains: D, E
Length: 8 amino acids
Theoretical weight: 1.01 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P21
Unit cell:
a: 37.78Å b: 54.526Å c: 65.124Å
α: 90° β: 96.26° γ: 90°
R-values:
R R work R free
0.196 0.196 0.212
Expression systems:
  • Escherichia coli
  • Not provided