› 3l46

X-ray diffraction
1.48Å resolution

Crystal structure of the second BRCT domain of epithelial cell transforming 2 (ECT2)

Released:
DOI: 10.2210/pdb3l46/pdb
PDB entry 3l46 coloured by chain, front view.
PDB entry 3l46 coloured by chain, side view.
PDB entry 3l46 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Nedyalkova L, Tempel W, Tong Y, Crombet L, Wang H, Guan X, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190685 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein ECT2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 112 amino acids
Theoretical weight: 13.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H8V3 (Residues: 268-361; Coverage: 10%)
Gene name: ECT2
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain

Ligands and Environments

1 bound ligand:
Ligand UNX 3 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 42.158Å b: 60.63Å c: 74.004Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.181 0.205
Expression system: Escherichia coli

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