› 3ljb

X-ray diffraction
2.4Å resolution

Structural basis of oligomerisation in the MxA stalk

Released:
DOI: 10.2210/pdb3ljb/pdb
PDB entry 3ljb coloured by chain, front view.
PDB entry 3ljb coloured by chain, side view.
PDB entry 3ljb coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of oligomerization in the stalk region of dynamin-like MxA.
Gao S, von der Malsburg A, Paeschke S, Behlke J, Haller O, Kochs G, Daumke O
Nature 465 502-6 (2010)
PMID: 20428112

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149011 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon-induced GTP-binding protein Mx1, N-terminally processed Chains: A, B
Molecule details ›
Chains: A, B
Length: 271 amino acids
Theoretical weight: 32.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20591 (Residues: 366-636; Coverage: 41%)
Gene name: MX1
Sequence domains:
Structure domains: Dynamin, middle domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P1
Unit cell:
a: 50.147Å b: 57.366Å c: 57.491Å
α: 65.82° β: 88.47° γ: 74.87°
R-values:
R R work R free
0.196 0.193 0.257
Expression system: Escherichia coli

Quick links

Citations

50 review citations

Interferon-stimulated genes: a complex web of host defenses.
Schneider et al. (2014)
49 more

10 mentions without citation

Building a fission machine--structural insights into dynamin assembly and activation.
Chappie et al. (2013)
9 more