3lqz

X-ray diffraction
3.25Å resolution

Crystal Structure of HLA-DP2

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-137850 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
HLA class II histocompatibility antigen, DP alpha 1 chain Chain: A
Molecule details ›
Chain: A
Length: 181 amino acids
Theoretical weight: 20.94 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P20036 (Residues: 32-212; Coverage: 78%)
Gene names: HLA-DP1A, HLA-DPA1, HLASB
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DP beta 1 chain Chain: B
Molecule details ›
Chain: B
Length: 212 amino acids
Theoretical weight: 24.46 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P04440 (Residues: 29-218; Coverage: 83%)
Gene names: HLA-DP1B, HLA-DPB1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P3121
Unit cell:
a: 157.282Å b: 157.282Å c: 61.805Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.219 0.217 0.251
Expression system: unidentified baculovirus