› 3lri

Solution NMR

Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I

Released:
DOI: 10.2210/pdb3lri/pdb
PDB entry 3lri coloured by chain, ensemble of 15 models, front view.
PDB entry 3lri coloured by chain, ensemble of 15 models, side view.
PDB entry 3lri coloured by chain, ensemble of 15 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I.
Laajoki LG, Francis GL, Wallace JC, Carver JA, Keniry MA
J Biol Chem 275 10009-15 (2000)
PMID: 10744677

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138312 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin-like growth factor I Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 9.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05019 (Residues: 40-118; Coverage: 45%)
Gene names: IBP1, IGF1
Sequence domains: Insulin/IGF/Relaxin family
Structure domains: Insulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND MOLECULAR DYNAMICS
Expression system: Escherichia coli

Quick links

Citations

8 citation in other articles

The interaction of insulin-like growth factor-I with the N-terminal domain of IGFBP-5.
Zesławski et al. (2001)
7 more

3 mentions without citation

Viral Hormones: Expanding Dimensions in Endocrinology.
Huang et al. (2019)
2 more