› 3lru

X-ray diffraction
1.85Å resolution

hPRP8 Non-Native Subdomain

Released:
DOI: 10.2210/pdb3lru/pdb
PDB entry 3lru coloured by chain, front view.
PDB entry 3lru coloured by chain, side view.
PDB entry 3lru coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Context-dependent remodeling of structure in two large protein fragments.
Schellenberg MJ, Ritchie DB, Wu T, Markin CJ, Spyracopoulos L, MacMillan AM
J Mol Biol 402 720-30 (2010)
PMID: 20713060

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180108 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pre-mRNA-processing-splicing factor 8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 160 amino acids
Theoretical weight: 18.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6P2Q9 (Residues: 1831-1990; Coverage: 7%)
Gene names: PRPC8, PRPF8
Sequence domains: PRP8 domain IV core

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P21
Unit cell:
a: 44.732Å b: 42.176Å c: 98.381Å
α: 90° β: 102° γ: 90°
R-values:
R R work R free
0.212 0.21 0.254
Expression system: Escherichia coli

Quick links

Citations

5 citation in other articles

Design of structurally distinct proteins using strategies inspired by evolution.
Jacobs et al. (2016)
4 more

2 mentions without citation

ChSeq: A database of chameleon sequences.
Li et al. (2015)
1 more