› 3lse

X-ray diffraction
2.69Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-126137 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-9 Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 15.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00182 (Residues: 6-148; Coverage: 40%)
Gene name: LGALS9
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM16
Spacegroup: P41212
Unit cell:
a: 32.387Å b: 32.387Å c: 232.208Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.223 0.352
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code.
Solís et al. (2015)
5 more

1 mention without citation

Glycomimetics for the inhibition and modulation of lectins.
Leusmann et al. (2023)