Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Transforming protein RhoA and IpgB2 (preferred)
PDBe Complex ID:
PDB-CPX-158286 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transforming protein RhoA
Molecule details ›
Chains: A, B
Length: 185 amino acids
Theoretical weight: 20.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 185 amino acids
Theoretical weight: 20.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P61586 (Residues: 2-181; Coverage: 93%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
IpgB2
Molecule details ›
Chains: F, G
Length: 192 amino acids
Theoretical weight: 21.94 KDa
Source organism: Shigella flexneri
Expression system: Escherichia coli
UniProt:
Sequence domains: IpaB/EvcA family
Structure domains: SopE-like GEF fold
Length: 192 amino acids
Theoretical weight: 21.94 KDa
Source organism: Shigella flexneri
Expression system: Escherichia coli
UniProt:
- Canonical: Q9AJW7 (Residues: 1-188; Coverage: 100%)
Sequence domains: IpaB/EvcA family
Structure domains: SopE-like GEF fold
