› 3m03

X-ray diffraction
2.5Å resolution

Crystal structure of human Orc6 fragment

Released:
DOI: 10.2210/pdb3m03/pdb
PDB entry 3m03 coloured by chain, front view.
PDB entry 3m03 coloured by chain, side view.
PDB entry 3m03 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB.
Liu S, Balasov M, Wang H, Wu L, Chesnokov IN, Liu Y
Proc Natl Acad Sci U S A 108 7373-8 (2011)
PMID: 21502537

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195279 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Origin recognition complex subunit 6 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 95 amino acids
Theoretical weight: 10.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y5N6 (Residues: 94-187; Coverage: 37%)
Gene names: ORC6, ORC6L
Structure domains: Cyclin-like

Ligands and Environments

2 bound ligands:
Ligand MES 1 x MES
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P4
Unit cell:
a: 104.571Å b: 104.571Å c: 30.936Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.226 0.266
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Mechanisms for initiating cellular DNA replication.
Costa et al. (2013)
10 more

2 mentions without citation

Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB.
Liu et al. (2011)
1 more