› 3mgm

X-ray diffraction
1.8Å resolution

Crystal structure of human NUDT16

Released:
DOI: 10.2210/pdb3mgm/pdb
PDB entry 3mgm coloured by chain, front view.
PDB entry 3mgm coloured by chain, side view.
PDB entry 3mgm coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yan J, Lu G, Zhang J, Qi J, Li Z, Gao F

Function and Biology Details

Reactions catalysed: 
5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] + H(2)O = N(7)-methylguanosine 5'-diphosphate + 5'-phospho-[mRNA]
IDP + H(2)O = IMP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188436 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
U8 snoRNA-decapping enzyme Chains: A, B
Molecule details ›
Chains: A, B
Length: 200 amino acids
Theoretical weight: 21.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96DE0 (Residues: 1-195; Coverage: 100%)
Gene name: NUDT16
Sequence domains: NUDIX domain
Structure domains: Nucleoside Triphosphate Pyrophosphohydrolase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 44.412Å b: 79.153Å c: 97.422Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.184 0.2
Expression system: Escherichia coli

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