3n00

X-ray diffraction
2.6Å resolution

Crystal Structure of a deletion mutant of human Reverba ligand binding domain bound with an NCoR ID1 peptide determined to 2.60A

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-130925 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear receptor subfamily 1 group D member 1 Chain: A
Molecule details ›
Chain: A
Length: 245 amino acids
Theoretical weight: 27.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P20393 (Residues: 281-614; Coverage: 38%)
Gene names: EAR1, HREV, NR1D1, THRAL
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
Nuclear receptor corepressor 1 Chain: B
Molecule details ›
Chain: B
Length: 21 amino acids
Theoretical weight: 2.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O75376 (Residues: 2045-2065; Coverage: 1%)
Gene names: KIAA1047, NCOR1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: R32
Unit cell:
a: 112.55Å b: 112.55Å c: 103.833Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.199 0.266
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided