Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- GPCR, family 2, calcitonin receptor family
- GPCR, family 2, extracellular hormone receptor domain
- GPCR, family 2, calcitonin gene-related peptide, type 1 receptor
- Receptor activity modifying protein
- GPCR family 2, extracellular hormone receptor domain superfamily
- RAMP domain superfamily
- GPCR, family 2, secretin-like, conserved site
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
CGRP receptor complex (preferred)
PDBe Complex ID:
PDB-CPX-130163 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calcitonin gene-related peptide type 1 receptor
Molecule details ›
Chains: A, B, C, J
Length: 115 amino acids
Theoretical weight: 13.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Hormone receptor domain
Structure domains: GPCR, family 2, extracellular hormone receptor domain
Length: 115 amino acids
Theoretical weight: 13.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q16602 (Residues: 23-133; Coverage: 25%)
Sequence domains: Hormone receptor domain
Structure domains: GPCR, family 2, extracellular hormone receptor domain
Receptor activity-modifying protein 1
Molecule details ›
Chains: D, E, F, R
Length: 96 amino acids
Theoretical weight: 11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Receptor activity modifying family
Structure domains: Receptor activity modifying family
Length: 96 amino acids
Theoretical weight: 11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O60894 (Residues: 26-117; Coverage: 75%)
Sequence domains: Receptor activity modifying family
Structure domains: Receptor activity modifying family
