Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-116610 (preferred)
Entry contents:
3 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (5 distinct):
Recombining binding protein suppressor of hairless
Molecule details ›
Notch 1 intracellular domain
Molecule details ›
Chains: B, E
Length: 256 amino acids
Theoretical weight: 27.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Ankyrin repeat-containing domain
Length: 256 amino acids
Theoretical weight: 27.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P46531 (Residues: 1872-2126; Coverage: 10%)
Sequence domains:
Structure domains: Ankyrin repeat-containing domain
Mastermind-like protein 1
Molecule details ›
Chains: C, F
Length: 63 amino acids
Theoretical weight: 7.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: MamL-1 domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 63 amino acids
Theoretical weight: 7.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q92585 (Residues: 13-74; Coverage: 6%)
Sequence domains: MamL-1 domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-C
Spacegroup:
C2
Expression system: Escherichia coli
