3ndq

X-ray diffraction
1.93Å resolution

Structure of Human TFIIS Domain II

Released:
Source organism: Homo sapiens
Entry authors: Hu XP, Averell G, Ye XY, Hou J, Luo H

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-149891 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription elongation factor A protein 1 Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P23193 (Residues: 131-232; Coverage: 34%)
Gene names: GTF2S, TCEA1, TFIIS
Sequence domains: Transcription factor S-II (TFIIS), central domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: I222
Unit cell:
a: 59.27Å b: 60.75Å c: 61.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.166 0.208
Expression system: Escherichia coli BL21(DE3)