› 3nzl

X-ray diffraction
1.2Å resolution

Crystal Structure of the N-terminal domain of DNA-binding protein SATB1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4435B

Released:
DOI: 10.2210/pdb3nzl/pdb
PDB entry 3nzl coloured by chain, front view.
PDB entry 3nzl coloured by chain, side view.
PDB entry 3nzl coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Forouhar F, Abashidze M, Seetharaman J, Kuzin AP, Patel P, Xiao R, Ciccosanti C, Shastry R, Everett JK, Nair R, Acton TB, Rost B, Montelione GT, Hunt JF, Tong L, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169634 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-binding protein SATB1 Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 9.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q01826 (Residues: 179-250; Coverage: 9%)
Gene name: SATB1
Sequence domains: CUT1-like DNA-binding domain of SATB
Structure domains: SATB, CULT domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P212121
Unit cell:
a: 33.926Å b: 43.48Å c: 42.461Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.15 0.148 0.177
Expression system: Escherichia coli BL21(DE3)

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