› 3o9u

X-ray diffraction
3.2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137077 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural protein 1 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 152 amino acids
Theoretical weight: 16.99 KDa
Source organism: Influenza A virus (A/reassortant/IVR108(Sydney/5/1995 x Puerto Rico/8/1934)(H3N2))
Expression system: Escherichia coli
UniProt:
  • Canonical: P03496 (Residues: 79-230; Coverage: 66%)
Gene name: NS
Sequence domains: Influenza non-structural protein (NS1)
Structure domains: Influenza virus non-structural protein, effector domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P64
Unit cell:
a: 114.124Å b: 114.124Å c: 199.289Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.175 0.174 0.222
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Induction and evasion of type I interferon responses by influenza viruses.
García-Sastre A. (2011)
9 more

4 mentions without citation

A transient homotypic interaction model for the influenza A virus NS1 protein effector domain.
Kerry et al. (2011)
3 more