› 3oax

X-ray diffraction
2.6Å resolution

Crystal structure of bovine rhodopsin with beta-ionone

Released:
DOI: 10.2210/pdb3oax/pdb
PDB entry 3oax coloured by chain, front view.
PDB entry 3oax coloured by chain, side view.
PDB entry 3oax coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Binding of more than one retinoid to visual opsins.
Makino CL, Riley CK, Looney J, Crouch RK, Okada T
Biophys J 99 2366-73 (2010)
PMID: 20923672

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136077 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Rhodopsin Chains: A, B
Molecule details ›
Chains: A, B
Length: 349 amino acids
Theoretical weight: 39.06 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02699 (Residues: 1-348; Coverage: 100%)
Gene name: RHO
Sequence domains:
Structure domains: Rhodopsin 7-helix transmembrane proteins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
8 bound ligands:
Ligand RET 2 x RET
Ligand PLM 4 x PLM
Ligand HG 6 x HG
Ligand ZN 7 x ZN
Ligand 4E6 2 x 4E6
Ligand HTG 4 x HTG
Ligand ID3 2 x ID3
Ligand HTO 1 x HTO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P41
Unit cell:
a: 96.99Å b: 96.99Å c: 149.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.262

Quick links

Citations

4 review citations

Chemistry of the retinoid (visual) cycle.
Kiser et al. (2014)
3 more

14 mentions without citation

Diversity and modularity of G protein-coupled receptor structures.
Katritch et al. (2012)
13 more