3obu

X-ray diffraction
1.6Å resolution

Crystal structure of the Tsg101 UEV domain in complex with a HIV-1 PTAP peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-180774 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor susceptibility gene 101 protein Chain: A
Molecule details ›
Chain: A
Length: 146 amino acids
Theoretical weight: 16.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99816 (Residues: 2-145; Coverage: 36%)
Gene name: TSG101
Sequence domains: UEV domain
Structure domains: Ubiquitin Conjugating Enzyme
Gag polyprotein Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 966 Da
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: Q72497 (Residues: 453-461; Coverage: 2%)
Gene name: gag

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P212121
Unit cell:
a: 33.526Å b: 45.769Å c: 85.446Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.199 0.236
Expression systems:
  • Escherichia coli
  • Not provided