3oq9

X-ray diffraction
6.8Å resolution

Structure of the FAS/FADD death domain assembly

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-150480 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor necrosis factor receptor superfamily member 6 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 86 amino acids
Theoretical weight: 10.16 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P25446 (Residues: 223-308; Coverage: 28%)
Gene names: Apt1, Fas, Tnfrsf6
Sequence domains: Death domain
FAS-associated death domain protein Chains: H, I, J, K, L
Molecule details ›
Chains: H, I, J, K, L
Length: 100 amino acids
Theoretical weight: 11.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13158 (Residues: 93-184; Coverage: 44%)
Gene names: FADD, GIG3, MORT1
Sequence domains: Death domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2221
Unit cell:
a: 135.204Å b: 144.447Å c: 131.574Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.343 0.343 0.354
Expression system: Escherichia coli BL21(DE3)