› 3p5q

X-ray diffraction
2Å resolution

Ferric R-state human aquomethemoglobin

Released:
DOI: 10.2210/pdb3p5q/pdb
PDB entry 3p5q coloured by chain, front view.
PDB entry 3p5q coloured by chain, side view.
PDB entry 3p5q coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human R-state aquomethemoglobin at 2.0 Å resolution.
Yi J, Thomas LM, Richter-Addo GB
Acta Crystallogr Sect F Struct Biol Cryst Commun 67 647-51 (2011)
PMID: 21636902

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159519 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P69905 (Residues: 2-142; Coverage: 99%)
Gene names: HBA1, HBA2
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chain: B
Molecule details ›
Chain: B
Length: 146 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 2 x HEM
Ligand MBN 3 x MBN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P41212
Unit cell:
a: 53.546Å b: 53.546Å c: 192.76Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.221 0.267

Quick links

Citations

5 citation in other articles

Nitrite reductase activity and inhibition of H₂S biogenesis by human cystathionine ß-synthase.
Gherasim et al. (2014)
4 more

16 mentions without citation

Structure of the hemoglobin-IsdH complex reveals the molecular basis of iron capture by Staphylococcus aureus.
Dickson et al. (2014)
15 more