› 3pd7

X-ray diffraction
1.26Å resolution

Crystal Structure of the Sixth BRCT Domain of Human TopBP1

Released:
DOI: 10.2210/pdb3pd7/pdb
PDB entry 3pd7 coloured by chain, front view.
PDB entry 3pd7 coloured by chain, side view.
PDB entry 3pd7 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lee J, Xu C, Cui G, Thompson JR, Mer G

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187682 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA topoisomerase 2-binding protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 107 amino acids
Theoretical weight: 12.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92547 (Residues: 893-994; Coverage: 7%)
Gene names: KIAA0259, TOPBP1
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P2
Unit cell:
a: 32.877Å b: 37.911Å c: 79.43Å
α: 90° β: 89.99° γ: 90°
R-values:
R R work R free
0.114 0.114 0.144
Expression system: Escherichia coli BL21(DE3)

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