› 3pds

X-ray diffraction
3.5Å resolution

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132941 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-2 adrenergic receptor; Endolysin Chain: A
Molecule details ›
Chain: A
Length: 458 amino acids
Theoretical weight: 52.45 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P07550 (Residues: 25-230, 264-348; Coverage: 71%)
  • Canonical: P00720 (Residues: 2-162; Coverage: 98%)
Gene names: ADRB2, ADRB2R, B2AR, E
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand ERC 1 x ERC
Ligand CLR 1 x CLR
Ligand SO4 6 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P21212
Unit cell:
a: 282.44Å b: 40.04Å c: 65.21Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.241 0.238 0.283
Expression system: Spodoptera frugiperda

Quick links

Citations

108 review citations

Molecular signatures of G-protein-coupled receptors.
Venkatakrishnan et al. (2013)
107 more

61 mentions without citation

Structure-function of the G protein-coupled receptor superfamily.
Katritch et al. (2013)
60 more