Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Superantigen, staphylococcal/streptococcal toxin, bacterial
- Anaphylatoxin, complement system domain
- Staphylococcus aureus exotoxin
- Netrin module, non-TIMP type
- Alpha-macroglobulin, receptor-binding
- Alpha-macroglobulin, receptor-binding domain superfamily
- Anaphylatoxin/fibulin
- Alpha-2-macroglobulin, bait region domain
18 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-112504 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Complement C5
Molecule details ›
Chains: A, C
Length: 1676 amino acids
Theoretical weight: 188.51 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 1676 amino acids
Theoretical weight: 188.51 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P01031 (Residues: 1-1676; Coverage: 100%)
Sequence domains:
- Macroglobulin domain MG1
- MG2 domain
- Macroglobulin domain MG3
- Macroglobulin domain MG4
- Alpha-2-macroglobulin bait region domain
- Anaphylotoxin-like domain
- Alpha-2-macroglobulin family
- A-macroglobulin TED domain
- Complement component 5, CUB domain
- A-macroglobulin receptor binding domain
- UNC-6/NTR/C345C module
Cobra venom factor
Molecule details ›
Chains: B, D
Length: 1642 amino acids
Theoretical weight: 184.73 KDa
Source organism: Naja kaouthia
UniProt:
Length: 1642 amino acids
Theoretical weight: 184.73 KDa
Source organism: Naja kaouthia
UniProt:
- Canonical: Q91132 (Residues: 1-1642; Coverage: 100%)
- Macroglobulin domain MG1
- MG2 domain
- Macroglobulin domain MG3
- Macroglobulin domain MG4
- Alpha-2-macroglobulin bait region domain
- Anaphylotoxin-like domain
- Alpha-2-macroglobulin family
- A-macroglobulin TED domain
- A-macroglobulin receptor binding domain
- UNC-6/NTR/C345C module
- Complement component 3, CUB domain 1
- Complement component 3, CUB domain 2
Staphylococcal superantigen-like OB-fold domain-containing protein
Molecule details ›
Chains: X, Y
Length: 231 amino acids
Theoretical weight: 26.01 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
Length: 231 amino acids
Theoretical weight: 26.01 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
- Canonical: D3JIB2 (Residues: 1-231; Coverage: 100%)
