› 3q04

X-ray diffraction
1.8Å resolution

Crystal structure of the apo-form of human CK2 alpha at pH 8.5

Released:
DOI: 10.2210/pdb3q04/pdb
PDB entry 3q04 coloured by chain, front view.
PDB entry 3q04 coloured by chain, side view.
PDB entry 3q04 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Battistutta R, Ranchio A, Papinutto E

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159383 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase II subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 328 amino acids
Theoretical weight: 39.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68400 (Residues: 3-330; Coverage: 84%)
Gene names: CK2A1, CSNK2A1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand SO4 3 x SO4
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 58.686Å b: 46.065Å c: 63.675Å
α: 90° β: 111.51° γ: 90°
R-values:
R R work R free
0.164 0.162 0.216
Expression system: Escherichia coli

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