› 3q2l

X-ray diffraction
2.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140757 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadherin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 213 amino acids
Theoretical weight: 23.28 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P09803 (Residues: 157-369; Coverage: 25%)
Gene name: Cdh1
Sequence domains: Cadherin domain
Structure domains: Cadherins

Ligands and Environments

2 bound ligands:
Ligand CA 8 x CA
Ligand 1PE 2 x 1PE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: C222
Unit cell:
a: 142.708Å b: 168.948Å c: 131.071Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.214 0.245
Expression system: Escherichia coli BL21

Quick links

Citations

62 review citations

Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling.
Takeichi M. (2014)
61 more

2 mentions without citation

The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins.
Harrison et al. (2011)
1 more