› 3q2u

X-ray diffraction
1.85Å resolution

Structure of Human Glioma Pathogenesis-related Protein 1 Reveals Unique loops and surface motifs.

Released:
DOI: 10.2210/pdb3q2u/pdb
PDB entry 3q2u coloured by chain, front view.
PDB entry 3q2u coloured by chain, side view.
PDB entry 3q2u coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural studies of human glioma pathogenesis-related protein 1.
Asojo OA, Koski RA, Bonafé N
Acta Crystallogr D Biol Crystallogr 67 847-55 (2011)
PMID: 21931216

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155702 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glioma pathogenesis-related protein 1 Chain: A
Molecule details ›
Chain: A
Length: 205 amino acids
Theoretical weight: 23.32 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P48060 (Residues: 22-220; Coverage: 81%)
Gene names: GLIPR, GLIPR1, RTVP1
Sequence domains: Cysteine-rich secretory protein family
Structure domains: CAP

Ligands and Environments

1 bound ligand:
Ligand GOL 4 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCE ULTRA
Spacegroup: P21212
Unit cell:
a: 85.077Å b: 79.532Å c: 38.849Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.137 0.134 0.184
Expression system: Komagataella pastoris

Quick links

Citations

4 review citations

Emerging Insights into the Functions of Pathogenesis-Related Protein 1.
Breen et al. (2017)
3 more

4 mentions without citation

Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs.
Kelleher et al. (2014)
3 more