3qcv

X-ray diffraction
2.51Å resolution

Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (18:2)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-134636 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein Chains: H, I
Molecule details ›
Chains: H, I
Length: 223 amino acids
Theoretical weight: 24.04 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q6N089 (Residues: 20-243; Coverage: 49%)
Gene name: DKFZp686P15220
Sequence domains:
Structure domains: Immunoglobulins
Immunoglobulin kappa constant Chains: L, M
Molecule details ›
Chains: L, M
Length: 218 amino acids
Theoretical weight: 23.84 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01834 (Residues: 1-106; Coverage: 99%)
Gene name: IGKC
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2221
Unit cell:
a: 86.98Å b: 183.131Å c: 127.498Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.215 0.266
Expression system: Cricetulus griseus