› 3qik

X-ray diffraction
2.28Å resolution

Crystal structure of the first PDZ domain of PREX1

Released:
DOI: 10.2210/pdb3qik/pdb
PDB entry 3qik coloured by chain, front view.
PDB entry 3qik coloured by chain, side view.
PDB entry 3qik coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Shen L, Tong Y, Tempel W, Li Y, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186196 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Chain: A
Molecule details ›
Chain: A
Length: 101 amino acids
Theoretical weight: 11.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TCU6 (Residues: 607-706; Coverage: 6%)
Gene names: KIAA1415, PREX1
Structure domains: Pdz3 Domain

Ligands and Environments

1 bound ligand:
Ligand UNX 8 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P3121
Unit cell:
a: 78.135Å b: 78.135Å c: 54.691Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.244 0.242 0.269
Expression system: Escherichia coli

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