› 3qir

X-ray diffraction
2.45Å resolution

Crystal structure of PIWIL2 PAZ domain

Released:
DOI: 10.2210/pdb3qir/pdb
PDB entry 3qir coloured by chain, front view.
PDB entry 3qir coloured by chain, side view.
PDB entry 3qir coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dong A, Xu C, Bian C, Wernimont AK, Kania J, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Min J, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186184 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Piwi-like protein 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 148 amino acids
Theoretical weight: 17.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8TC59 (Residues: 386-533; Coverage: 15%)
Gene names: HILI, PIWIL2
Sequence domains: PAZ domain
Structure domains: paz domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 41.548Å b: 139.291Å c: 224.934Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.242 0.272
Expression system: Escherichia coli BL21(DE3)

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