› 3qjf

X-ray diffraction
2.4Å resolution

Crystal structure of the 2B4 TCR

Released:
DOI: 10.2210/pdb3qjf/pdb
PDB entry 3qjf coloured by chain, front view.
PDB entry 3qjf coloured by chain, side view.
PDB entry 3qjf coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
Newell EW, Ely LK, Kruse AC, Reay PA, Rodriguez SN, Lin AE, Kuhns MS, Garcia KC, Davis MM
J Immunol 186 5823-32 (2011)
PMID: 21490152

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-208596 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T cell receptor alpha chain constant Chains: A, C
Molecule details ›
Chains: A, C
Length: 207 amino acids
Theoretical weight: 22.81 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01848 (Residues: 1-93; Coverage: 66%)
Gene names: TCRA, TRAC
Sequence domains: Domain of unknown function (DUF1968)
Structure domains: Immunoglobulins
2B4 beta chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 244 amino acids
Theoretical weight: 27.85 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P6522
Unit cell:
a: 93.85Å b: 93.85Å c: 388.751Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.21 0.259
Expression system: Escherichia coli

Quick links

Citations

9 review citations

γδ T cells: first line of defense and beyond.
Chien et al. (2014)
8 more

6 mentions without citation

Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
Newell et al. (2011)
5 more