› 3qki

X-ray diffraction
1.92Å resolution

Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7

Released:
DOI: 10.2210/pdb3qki/pdb
PDB entry 3qki coloured by chain, front view.
PDB entry 3qki coloured by chain, side view.
PDB entry 3qki coloured by chain, top view.
Source organism: Plasmodium falciparum 3D7
Entry authors: Gileadi T, Wernimont AK, Hutchinson A, Weadge J, Cossar D, Lew J, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Hui R, Hills T, Pizarro JC, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
Alpha-D-glucose 6-phosphate = beta-D-fructofuranose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184815 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate isomerase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 597 amino acids
Theoretical weight: 69.66 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8ILA4 (Residues: 1-579; Coverage: 100%)
Gene name: PF3D7_1436000
Sequence domains: Phosphoglucose isomerase
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2
Unit cell:
a: 138.444Å b: 233.003Å c: 72.794Å
α: 90° β: 91.4° γ: 90°
R-values:
R R work R free
0.175 0.174 0.207
Expression system: Escherichia coli BL21(DE3)

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