› 3qrd

X-ray diffraction
2.19Å resolution

Crystal structure of L68V mutant of human cystatin C

Released:
DOI: 10.2210/pdb3qrd/pdb
PDB entry 3qrd coloured by chain, front view.
PDB entry 3qrd coloured by chain, side view.
PDB entry 3qrd coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Orlikowska M, Borek D, Otwinowski Z, Skowron P, Szymanska A

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo octamer
Assembly name:
PDBe Complex ID:
PDB-CPX-133889 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cystatin-C Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 120 amino acids
Theoretical weight: 13.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01034 (Residues: 27-146; Coverage: 100%)
Gene name: CST3
Sequence domains: Cystatin domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

1 bound ligand:
Ligand PEG 6 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 103.123Å b: 89.876Å c: 65.154Å
α: 90° β: 107.03° γ: 90°
R-values:
R R work R free
0.218 0.214 0.293
Expression system: Escherichia coli

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