› 3qwl

X-ray diffraction
1.9Å resolution

Crystal structure of human TBC1 domain family member 7

Released:
DOI: 10.2210/pdb3qwl/pdb
PDB entry 3qwl coloured by chain, front view.
PDB entry 3qwl coloured by chain, side view.
PDB entry 3qwl coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Guan X, Tempel W, Tong Y, Wernimont AK, Landry R, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192804 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TBC1 domain family member 7 Chain: A
Molecule details ›
Chain: A
Length: 294 amino acids
Theoretical weight: 34.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9P0N9 (Residues: 1-293; Coverage: 100%)
Gene names: HSPC239, TBC1D7, TBC7
Sequence domains: Rab-GTPase-TBC domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand UNX 4 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 34.574Å b: 83.984Å c: 87.684Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.211 0.258
Expression system: Escherichia coli BL21(DE3)

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