› 3rez

X-ray diffraction
2.35Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146512 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Platelet glycoprotein IX; Platelet glycoprotein Ib beta chain Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 129 amino acids
Theoretical weight: 14.09 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P14770 (Residues: 20-21, 45-53, 65-77, 92-103; Coverage: 22%)
  • Canonical: P13224 (Residues: 28-45, 58-68, 82-95, 108-143; Coverage: 44%)
Gene names: GP1BB, GP9
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

4 bound ligands:
Ligand NAG 5 x NAG
Ligand PEG 7 x PEG
Ligand FUL 1 x FUL
Ligand MAN 1 x MAN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P3121
Unit cell:
a: 72.01Å b: 72.01Å c: 171.731Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.214 0.211 0.259
Expression system: Cricetulus griseus

Quick links

Citations

8 review citations

von Willebrand factor, Jedi knight of the bloodstream.
Springer TA. (2014)
7 more

1 mention without citation

Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera.
McEwan et al. (2011)