› 3rg0

X-ray diffraction
2.57Å resolution

Structural and functional relationships between the lectin and arm domains of calreticulin

Released:
DOI: 10.2210/pdb3rg0/pdb
PDB entry 3rg0 coloured by chain, front view.
PDB entry 3rg0 coloured by chain, side view.
PDB entry 3rg0 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural and functional relationships between the lectin and arm domains of calreticulin.
Pocanschi CL, Kozlov G, Brockmeier U, Brockmeier A, Williams DB, Gehring K
J Biol Chem 286 27266-77 (2011)
PMID: 21652723

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146879 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calreticulin Chain: A
Molecule details ›
Chain: A
Length: 332 amino acids
Theoretical weight: 38.14 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P14211 (Residues: 18-238, 273-368; Coverage: 79%)
Gene name: Calr
Sequence domains: Calreticulin family
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P212121
Unit cell:
a: 43.062Å b: 71.701Å c: 108.386Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.234 0.286
Expression system: Escherichia coli BL21

Quick links

Citations

5 review citations

Calreticulin in the immune system: ins and outs.
Raghavan et al. (2013)
4 more

9 mentions without citation

Calnexin cycle - structural features of the ER chaperone system.
Kozlov et al. (2020)
8 more