› 3rgh

X-ray diffraction
2.44Å resolution

Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens

Released:
DOI: 10.2210/pdb3rgh/pdb
PDB entry 3rgh coloured by chain, front view.
PDB entry 3rgh coloured by chain, side view.
PDB entry 3rgh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens.
Page RC, Clark JG, Misra S
Acta Crystallogr Sect F Struct Biol Cryst Commun 67 871-6 (2011)
PMID: 21821884

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149204 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Filamin-A Chains: A, B
Molecule details ›
Chains: A, B
Length: 100 amino acids
Theoretical weight: 10.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P21333 (Residues: 1158-1252; Coverage: 4%)
Gene names: FLN, FLN1, FLNA
Sequence domains: Filamin/ABP280 repeat
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand ACT 2 x ACT
1 modified residue:
Ligand CME 2 x CME

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P212121
Unit cell:
a: 36.453Å b: 50.549Å c: 107.172Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.229 0.279
Expression system: Escherichia coli

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Citations

4 citation in other articles

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Morikawa et al. (2014)
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5 mentions without citation

The TRIM-NHL protein LIN-41 controls the onset of developmental plasticity in Caenorhabditis elegans.
Tocchini et al. (2014)
4 more