› 3rnj

X-ray diffraction
1.5Å resolution

Crystal structure of the SH3 domain from IRSp53 (BAIAP2)

Released:
DOI: 10.2210/pdb3rnj/pdb
PDB entry 3rnj coloured by chain, front view.
PDB entry 3rnj coloured by chain, side view.
PDB entry 3rnj coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Simister PC, Barilari M, Muniz JRC, Dente L, Knapp S, von Delft F, Filippakopoulos P, Vollmar M, Chaikuad A, Raynor J, Tregubova A, Arrowsmith CH, Edwards AM, Weigelt J, Bountra C, Feller SM, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194064 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BAR/IMD domain-containing adapter protein 2 Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 7.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UQB8 (Residues: 375-436; Coverage: 11%)
Gene name: BAIAP2
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

3 bound ligands:
Ligand EDT 1 x EDT
Ligand EDO 3 x EDO
Ligand IPA 1 x IPA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P212121
Unit cell:
a: 29.96Å b: 36.64Å c: 58.11Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.197 0.219
Expression system: Escherichia coli

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