› 3rt3

X-ray diffraction
2.01Å resolution

Complex of influenza virus protein with host anti-viral factor

Released:
DOI: 10.2210/pdb3rt3/pdb
PDB entry 3rt3 coloured by chain, front view.
PDB entry 3rt3 coloured by chain, side view.
PDB entry 3rt3 coloured by chain, top view.
Source organisms:
Entry authors: Wang XQ, Li L

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137085 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin-like protein ISG15 Chain: B
Molecule details ›
Chain: B
Length: 159 amino acids
Theoretical weight: 17.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05161 (Residues: 1-158; Coverage: 96%)
Gene names: G1P2, ISG15, UCRP
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Non-structural protein 1 Chain: C
Molecule details ›
Chain: C
Length: 109 amino acids
Theoretical weight: 12.71 KDa
Source organism: Influenza B virus (B/Lee/1940)
Expression system: Escherichia coli
UniProt:
  • Canonical: P03502 (Residues: 1-103; Coverage: 37%)
Gene name: NS
Sequence domains: Influenza B non-structural protein (NS1)
Structure domains: S15/NS1, RNA-binding

Ligands and Environments

1 bound ligand:
Ligand SIN 2 x SIN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 93.674Å b: 39.147Å c: 74.704Å
α: 90° β: 90.46° γ: 90°
R-values:
R R work R free
0.192 0.189 0.243
Expression system: Escherichia coli

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