› 3rwj

X-ray diffraction
2.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-158330 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 32.03 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9GJ77 (Residues: 24-299; Coverage: 80%)
Gene name: MHCI-B
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Virion infectivity factor Chain: C
Molecule details ›
Chain: C
Length: 8 amino acids
Theoretical weight: 1.03 KDa
Source organism: Simian immunodeficiency virus
Expression system: Not provided
UniProt:
  • Canonical: Q89490 (Residues: 66-73; Coverage: 4%)
Gene names: VIF, vif

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P2
Unit cell:
a: 67.96Å b: 44.6Å c: 80.63Å
α: 90° β: 96.94° γ: 90°
R-values:
R R work R free
0.213 0.21 0.256
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

3 review citations

Nonhuman primate models for HIV/AIDS vaccine development.
Sui et al. (2013)
2 more

1 mention without citation

Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex.
Morita et al. (2016)