› 3s6c

X-ray diffraction
2.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147490 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Beta-2-microglobulin; T-cell surface glycoprotein CD1e, soluble Chain: A
Molecule details ›
Chain: A
Length: 392 amino acids
Theoretical weight: 44.66 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
  • Canonical: P15812 (Residues: 32-303; Coverage: 74%)
Gene names: B2M, CD1E, CDABP0092, HDCMA22P
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: C2
Unit cell:
a: 206.289Å b: 45.93Å c: 65.628Å
α: 90° β: 91.48° γ: 90°
R-values:
R R work R free
0.243 0.241 0.296
Expression system: Homo sapiens

Quick links

Citations

20 review citations

The adaptable major histocompatibility complex (MHC) fold: structure and function of nonclassical and MHC class I-like molecules.
Adams et al. (2013)
19 more

6 mentions without citation

The CD1 size problem: lipid antigens, ligands, and scaffolds.
Ly et al. (2014)
5 more