Function and Biology Details
Reactions catalysed:
2 cob(II)alamin-[cyanocobalamin reductase] + 2 hydrogen cyanide + NADP(+) = 2 cyanocob(III)alamin + 2 [cyanocobalamin reductase] + NADPH
An alkylcobalamin + [alkylcobalamin reductase] + glutathione = cob(I)alamin-[alkylcobalamin reductase] + an S-alkylglutathione
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195250 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyanocobalamin reductase / alkylcobalamin dealkylase
Molecule details ›
Chains: A, B
Length: 252 amino acids
Theoretical weight: 29.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Methylmalonic aciduria and homocystinuria type C family
Length: 252 amino acids
Theoretical weight: 29.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9Y4U1 (Residues: 1-244; Coverage: 87%)
Sequence domains: Methylmalonic aciduria and homocystinuria type C family
