› 3sh4

X-ray diffraction
1.5Å resolution

Laminin G like domain 3 from human perlecan

Released:
DOI: 10.2210/pdb3sh4/pdb
PDB entry 3sh4 coloured by chain, front view.
PDB entry 3sh4 coloured by chain, side view.
PDB entry 3sh4 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the LG3 domain of endorepellin, an angiogenesis inhibitor.
Le BV, Kim H, Choi J, Kim JH, Hahn MJ, Lee C, Kim KK, Hwang HY
J Mol Biol 414 231-42 (2011)
PMID: 21996443

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161354 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LG3 peptide Chain: A
Molecule details ›
Chain: A
Length: 195 amino acids
Theoretical weight: 20.57 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P98160 (Residues: 4197-4391; Coverage: 5%)
Gene name: HSPG2
Sequence domains: Laminin G domain
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P212121
Unit cell:
a: 39.95Å b: 54.655Å c: 64.353Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.213

Quick links

Citations

5 review citations

Proteoglycan form and function: A comprehensive nomenclature of proteoglycans.
Iozzo et al. (2015)
4 more

8 mentions without citation

The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy.
Douglass et al. (2015)
7 more