3shu

X-ray diffraction
2.75Å resolution

Crystal structure of ZO-1 PDZ3

Released:
Source organism: Homo sapiens
Entry authors: Yu J, Pan L, Chen J, Yu H, Zhang M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-170447 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tight junction protein ZO-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 95 amino acids
Theoretical weight: 10.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07157 (Residues: 421-512; Coverage: 5%)
Gene names: TJP1, ZO1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P21
Unit cell:
a: 35.03Å b: 76.84Å c: 39.11Å
α: 90° β: 113.04° γ: 90°
R-values:
R R work R free
0.22 0.215 0.264
Expression system: Escherichia coli