› 3sp7

X-ray diffraction
1.4Å resolution

Crystal Structure of Bcl-xL bound to BM903

Released:
DOI: 10.2210/pdb3sp7/pdb
PDB entry 3sp7 coloured by chain, front view.
PDB entry 3sp7 coloured by chain, side view.
PDB entry 3sp7 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Meagher JL, Stuckey JA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170518 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bcl-2-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 172 amino acids
Theoretical weight: 19.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07817 (Residues: 1-209; Coverage: 73%)
Gene names: BCL2L, BCL2L1, BCLX
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand 03B 1 x 03B
Ligand ZN 4 x ZN
Ligand ACT 3 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P212121
Unit cell:
a: 41.627Å b: 54.891Å c: 79.569Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.164 0.185
Expression system: Escherichia coli

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