Function and Biology Details
Reactions catalysed:
S-adenosyl-L-methionine + a [histone H3]-L-lysine(9) = S-adenosyl-L-homocysteine + a [histone H3]-N(6)-methyl-L-lysine(9)
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-131546 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Histone-lysine N-methyltransferase EHMT1
Molecule details ›
Chains: A, B
Length: 285 amino acids
Theoretical weight: 32.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: SET domain
Length: 285 amino acids
Theoretical weight: 32.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9H9B1 (Residues: 982-1266; Coverage: 22%)
Sequence domains:
Structure domains: SET domain
DNA (cytosine-5)-methyltransferase 3A
Molecule details ›
Chains: P, Q
Length: 12 amino acids
Theoretical weight: 1.29 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Length: 12 amino acids
Theoretical weight: 1.29 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical: O88508 (Residues: 39-50; Coverage: 1%)
