Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Interleukin-21 receptor and Interleukin-21 (preferred)
PDBe Complex ID:
PDB-CPX-190748 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Interleukin-21 receptor
Molecule details ›
Chains: A, C, E, G, I, K, M, O
Length: 219 amino acids
Theoretical weight: 25.45 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Structure domains: Immunoglobulins
Length: 219 amino acids
Theoretical weight: 25.45 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9HBE5 (Residues: 20-232; Coverage: 41%)
Structure domains: Immunoglobulins
Interleukin-21
Molecule details ›
Chains: B, D, F, H, J, L, N, P
Length: 134 amino acids
Theoretical weight: 15.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Interleukin 15
Structure domains: Interleukin-15/Interleukin-21
Length: 134 amino acids
Theoretical weight: 15.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9HBE4 (Residues: 30-162; Coverage: 96%)
Sequence domains: Interleukin 15
Structure domains: Interleukin-15/Interleukin-21
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06DA
Spacegroup:
P212121
Expression systems:
- Homo sapiens
- Escherichia coli
