Function and Biology Details
Reaction catalysed:
Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
uPA-uPAR complex (preferred)
PDBe Complex ID:
PDB-CPX-133293 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Urokinase plasminogen activator surface receptor
Molecule details ›
Chain: U
Length: 283 amino acids
Theoretical weight: 31.46 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: u-PAR/Ly-6 domain
Structure domains: CD59
Length: 283 amino acids
Theoretical weight: 31.46 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
Q03405 (Residues: 23-305; Coverage: 90%)
Sequence domains: u-PAR/Ly-6 domain
Structure domains: CD59
Urokinase-type plasminogen activator long chain A
Molecule details ›
Chain: A
Length: 132 amino acids
Theoretical weight: 15 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: Kringle domain
Structure domains:
Length: 132 amino acids
Theoretical weight: 15 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical: P00749 (Residues: 21-152; Coverage: 32%)
Sequence domains: Kringle domain
Structure domains:
