› 3u8q

X-ray diffraction
1.97Å resolution

Crystal Structure of C-lobe of Bovine lactoferrin Complexed with Phenyl-Propanolamine at 1.97 A Resolution

Released:
DOI: 10.2210/pdb3u8q/pdb
PDB entry 3u8q coloured by chain, front view.
PDB entry 3u8q coloured by chain, side view.
PDB entry 3u8q coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Shukla PK, Gautam L, Sinha M, Kaur P, Sharma S, Singh TP

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150261 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 335 amino acids
Theoretical weight: 36.62 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P24627 (Residues: 361-695; Coverage: 49%)
Gene name: LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II
Lactotransferrin Chain: B
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 653 Da
Source organism: Bos taurus
UniProt:
  • Canonical: P24627 (Residues: 700-705; Coverage: 1%)
Gene name: LTF

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
6 bound ligands:
Ligand NAG 1 x NAG
Ligand FE 1 x FE
Ligand ZN 2 x ZN
Ligand CO3 1 x CO3
Ligand SO4 1 x SO4
Ligand NPU 1 x NPU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 62.437Å b: 49.918Å c: 65.486Å
α: 90° β: 107.26° γ: 90°
R-values:
R R work R free
0.179 0.179 0.198

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