› 3unp

X-ray diffraction
2.39Å resolution

Structure of human SUN2 SUN domain

Released:
DOI: 10.2210/pdb3unp/pdb
PDB entry 3unp coloured by chain, front view.
PDB entry 3unp coloured by chain, side view.
PDB entry 3unp coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope.
Zhou Z, Du X, Cai Z, Song X, Zhang H, Mizuno T, Suzuki E, Yee MR, Berezov A, Murali R, Wu SL, Karger BL, Greene MI, Wang Q
J Biol Chem 287 5317-26 (2012)
PMID: 22170055

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193730 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SUN domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 203 amino acids
Theoretical weight: 22.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UH99 (Residues: 520-717; Coverage: 28%)
Gene names: FRIGG, KIAA0668, RAB5IP, SUN2, UNC84B
Sequence domains:
Structure domains: Galactose-binding domain-like

Ligands and Environments

1 bound ligand:
Ligand ACE 1 x ACE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: R32
Unit cell:
a: 78.918Å b: 78.918Å c: 197.918Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.223 0.218 0.266
Expression system: Escherichia coli

Quick links

Citations

38 review citations

The nuclear lamins: flexibility in function.
Burke et al. (2013)
37 more

5 mentions without citation

Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope.
Zhou et al. (2012)
4 more