› 3vg4

X-ray diffraction
2.5Å resolution

Cadmium derivative of human LFABP

Released:
DOI: 10.2210/pdb3vg4/pdb
PDB entry 3vg4 coloured by chain, front view.
PDB entry 3vg4 coloured by chain, side view.
PDB entry 3vg4 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Utility of anion and cation combinations for phasing of protein structures.
Sharma A, Yogavel M, Sharma A
J Struct Funct Genomics 13 135-43 (2012)
PMID: 22562242

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139399 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, liver Chain: A
Molecule details ›
Chain: A
Length: 132 amino acids
Theoretical weight: 14.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07148 (Residues: 2-127; Coverage: 99%)
Gene names: FABP1, FABPL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand PLM 2 x PLM
Ligand CD 2 x CD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 29.938Å b: 57.535Å c: 72.925Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.23 0.31
Expression system: Escherichia coli

Quick links

Citations

1 review citation

L-FABP: A novel biomarker of kidney disease.
Xu et al. (2015)
3 other articles

1 mention without citation

Modulation of gene expression in contextual fear conditioning in the rat.
Federighi et al. (2013)